A Temperature Sensitive Variant of p53 Drives p53-Dependent MicroRNA Expression without Evidence of Widespread Post-Transcriptional Gene Silencing

The p53 tumour suppressor is a transcription factor that can regulate the expression of numerous genes including many encoding proteins and microRNAs (miRNAs). The predominant outcomes of a typical p53 response are the initiation of apoptotic cascades and the activation of cell cycle checkpoints. HT...

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Detalles Bibliográficos
Autores principales: Cabrita, Miguel A., Vanzyl, Erin J., Hamill, Jeff D., Pan, Elysia, Marcellus, Kristen A., Tolls, Victoria J., Alonzi, Rhea C., Pastic, Alyssa, Rambo, Teeghan M. E., Sayed, Hadil, McKay, Bruce C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739602/
https://www.ncbi.nlm.nih.gov/pubmed/26840126
http://dx.doi.org/10.1371/journal.pone.0148529

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