Structural basis of death domain signaling in the p75 neurotrophin receptor

Death domains (DDs) mediate assembly of oligomeric complexes for activation of downstream signaling pathways through incompletely understood mechanisms. Here we report structures of complexes formed by the DD of p75 neurotrophin receptor (p75(NTR)) with RhoGDI, for activation of the RhoA pathway, wi...

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Detalles Bibliográficos
Autores principales: Lin, Zhi, Tann, Jason Y, Goh, Eddy TH, Kelly, Claire, Lim, Kim Buay, Gao, Jian Fang, Ibanez, Carlos F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739766/
https://www.ncbi.nlm.nih.gov/pubmed/26646181
http://dx.doi.org/10.7554/eLife.11692

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739766/
https://www.ncbi.nlm.nih.gov/pubmed/26646181
http://dx.doi.org/10.7554/eLife.11692

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