Cargando…

A vocabulary of ancient peptides at the origin of folded proteins

The seemingly limitless diversity of proteins in nature arose from only a few thousand domain prototypes, but the origin of these themselves has remained unclear. We are pursuing the hypothesis that they arose by fusion and accretion from an ancestral set of peptides active as co-factors in RNA-depe...

Descripción completa

Detalles Bibliográficos
Autores principales: Alva, Vikram, Söding, Johannes, Lupas, Andrei N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739770/
https://www.ncbi.nlm.nih.gov/pubmed/26653858
http://dx.doi.org/10.7554/eLife.09410