A general strategy to construct small molecule biosensors in eukaryotes

Biosensors for small molecules can be used in applications that range from metabolic engineering to orthogonal control of transcription. Here, we produce biosensors based on a ligand-binding domain (LBD) by using a method that, in principle, can be applied to any target molecule. The LBD is fused to...

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Detalles Bibliográficos
Autores principales: Feng, Justin, Jester, Benjamin W, Tinberg, Christine E, Mandell, Daniel J, Antunes, Mauricio S, Chari, Raj, Morey, Kevin J, Rios, Xavier, Medford, June I, Church, George M, Fields, Stanley, Baker, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739774/
https://www.ncbi.nlm.nih.gov/pubmed/26714111
http://dx.doi.org/10.7554/eLife.10606

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739774/
https://www.ncbi.nlm.nih.gov/pubmed/26714111
http://dx.doi.org/10.7554/eLife.10606

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