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Biofilm-associated bacterial amyloids dampen inflammation in the gut: oral treatment with curli fibres reduces the severity of hapten-induced colitis in mice
BACKGROUND/OBJECTIVES: A disruption of epithelial barrier function can lead to intestinal inflammation. Toll-like receptor (TLR) 2 activation by microbial products promotes intestinal epithelial integrity and overall gut health. Several bacterial species, including enteric bacteria, actively produce...
Autores principales: | Oppong, Gertrude O, Rapsinski, Glenn J, Tursi, Sarah A, Biesecker, Steven G, Klein-Szanto, Andres J P, Goulian, Mark, McCauley, Christine, Healy, Catherine, Wilson, R Paul, Tükel, Cagla |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739805/ https://www.ncbi.nlm.nih.gov/pubmed/26855788 http://dx.doi.org/10.1038/npjbiofilms.2015.19 |
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