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Genome-wide association study and targeted metabolomics identifies sex-specific association of CPS1 with coronary artery disease
Metabolites derived from dietary choline and L-carnitine, such as trimethylamine N-oxide and betaine, have recently been identified as novel risk factors for atherosclerosis in mice and humans. We sought to identify genetic factors associated with plasma betaine levels and determine their effect on...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740183/ https://www.ncbi.nlm.nih.gov/pubmed/26822151 http://dx.doi.org/10.1038/ncomms10558 |