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Genome-wide association study and targeted metabolomics identifies sex-specific association of CPS1 with coronary artery disease

Metabolites derived from dietary choline and L-carnitine, such as trimethylamine N-oxide and betaine, have recently been identified as novel risk factors for atherosclerosis in mice and humans. We sought to identify genetic factors associated with plasma betaine levels and determine their effect on...

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Detalles Bibliográficos
Autores principales: Hartiala, Jaana A., Wilson Tang, W. H., Wang, Zeneng, Crow, Amanda L., Stewart, Alexandre F. R., Roberts, Robert, McPherson, Ruth, Erdmann, Jeanette, Willenborg, Christina, Hazen, Stanley L., Allayee, Hooman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740183/
https://www.ncbi.nlm.nih.gov/pubmed/26822151
http://dx.doi.org/10.1038/ncomms10558

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