Inactivation of nuclear GSK3β by Ser(389) phosphorylation promotes lymphocyte fitness during DNA double-strand break response

Variable, diversity and joining (V(D)J) recombination and immunoglobulin class switch recombination (CSR) are key processes in adaptive immune responses that naturally generate DNA double-strand breaks (DSBs) and trigger a DNA repair response. It is unclear whether this response is associated with d...

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Detalles Bibliográficos
Autores principales: Thornton, Tina M., Delgado, Pilar, Chen, Liang, Salas, Beatriz, Krementsov, Dimitry, Fernandez, Miriam, Vernia, Santiago, Davis, Roger J., Heimann, Ruth, Teuscher, Cory, Krangel, Michael S., Ramiro, Almudena R., Rincón, Mercedes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740185/
https://www.ncbi.nlm.nih.gov/pubmed/26822034
http://dx.doi.org/10.1038/ncomms10553

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740185/
https://www.ncbi.nlm.nih.gov/pubmed/26822034
http://dx.doi.org/10.1038/ncomms10553

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