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Metabolic Catastrophe in Mice Lacking Transferrin Receptor in Muscle

Transferrin receptor (Tfr1) is ubiquitously expressed, but its roles in non-hematopoietic cells are incompletely understood. We used a tissue-specific conditional knockout strategy to ask whether skeletal muscle required Tfr1 for iron uptake. We found that iron assimilation via Tfr1 was critical for...

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Detalles Bibliográficos
Autores principales:	Barrientos, Tomasa, Laothamatas, Indira, Koves, Timothy R., Soderblom, Erik J., Bryan, Miles, Moseley, M. Arthur, Muoio, Deborah M., Andrews, Nancy C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740293/ https://www.ncbi.nlm.nih.gov/pubmed/26870796 http://dx.doi.org/10.1016/j.ebiom.2015.09.041

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