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The Sigma-2 Receptor and Progesterone Receptor Membrane Component 1 are Different Binding Sites Derived From Independent Genes

The sigma-2 receptor (S2R) is a potential therapeutic target for cancer and neuronal diseases. However, the identity of the S2R has remained a matter of debate. Historically, the S2R has been defined as (1) a binding site with high affinity to 1,3-di-o-tolylguanidine (DTG) and haloperidol but not to...

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Detalles Bibliográficos
Autores principales:	Chu, Uyen B., Mavlyutov, Timur A., Chu, Ming-Liang, Yang, Huan, Schulman, Amanda, Mesangeau, Christophe, McCurdy, Christopher R., Guo, Lian-Wang, Ruoho, Arnold E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740303/ https://www.ncbi.nlm.nih.gov/pubmed/26870805 http://dx.doi.org/10.1016/j.ebiom.2015.10.017

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