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Export of malaria proteins requires co-translational processing of the PEXEL motif independent of phosphatidylinositol-3-phosphate binding

Plasmodium falciparum exports proteins into erythrocytes using the Plasmodium export element (PEXEL) motif, which is cleaved in the endoplasmic reticulum (ER) by plasmepsin V (PMV). A recent study reported that phosphatidylinositol-3-phosphate (PI(3)P) concentrated in the ER binds to PEXEL motifs an...

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Detalles Bibliográficos
Autores principales:	Boddey, Justin A., O'Neill, Matthew T., Lopaticki, Sash, Carvalho, Teresa G., Hodder, Anthony N., Nebl, Thomas, Wawra, Stephan, van West, Pieter, Ebrahimzadeh, Zeinab, Richard, Dave, Flemming, Sven, Spielmann, Tobias, Przyborski, Jude, Babon, Jeff J., Cowman, Alan F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740378/ https://www.ncbi.nlm.nih.gov/pubmed/26832821 http://dx.doi.org/10.1038/ncomms10470

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