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Impaired intracellular trafficking defines early Parkinson's disease

Parkinson's disease (PD) is an insidious and incurable neurodegenerative disease, and represents a significant cost to individuals, carers, and ageing societies. It is defined at post-mortem by the loss of dopamine neurons in the substantia nigra together with the presence of Lewy bodies and Le...

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Detalles Bibliográficos
Autores principales: Hunn, Benjamin H.M., Cragg, Stephanie J., Bolam, J. Paul, Spillantini, Maria-Grazia, Wade-Martins, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Applied Science Publishing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740565/
https://www.ncbi.nlm.nih.gov/pubmed/25639775
http://dx.doi.org/10.1016/j.tins.2014.12.009