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Cofilin-induced cooperative conformational changes of actin subunits revealed using cofilin-actin fusion protein
To investigate cooperative conformational changes of actin filaments induced by cofilin binding, we engineered a fusion protein made of Dictyostelium cofilin and actin. The filaments of the fusion protein were functionally similar to actin filaments bound with cofilin in that they did not bind rhoda...
Autores principales: | Umeki, Nobuhisa, Hirose, Keiko, Uyeda, Taro Q. P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740740/ https://www.ncbi.nlm.nih.gov/pubmed/26842224 http://dx.doi.org/10.1038/srep20406 |
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