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HIF-2α promotes epithelial-mesenchymal transition through regulating Twist2 binding to the promoter of E-cadherin in pancreatic cancer

BACKGROUND: Epithelial-mesenchymal transition (EMT) is a dedifferentiation process that mainly involves in mesenchymal marker upregulation, epithelial maker downregulation and cell polarity loss. Related hypoxia factors play a crucial role in EMT, however, it remains few evidence to clarify the role...

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Detalles Bibliográficos
Autores principales:	Yang, Jian, Zhang, Xu, Zhang, Yi, Zhu, Dongming, Zhang, Lifeng, Li, Ye, Zhu, Yanbo, Li, Dechun, Zhou, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741030/ https://www.ncbi.nlm.nih.gov/pubmed/26842802 http://dx.doi.org/10.1186/s13046-016-0298-y

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