Transgelin increases metastatic potential of colorectal cancer cells in vivo and alters expression of genes involved in cell motility

BACKGROUND: Transgelin is an actin-binding protein that promotes motility in normal cells. Although the role of transgelin in cancer is controversial, a number of studies have shown that elevated levels correlate with aggressive tumor behavior, advanced stage, and poor prognosis. Here we sought to d...

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Detalles Bibliográficos
Autores principales: Zhou, Hui-min, Fang, Yuan-yuan, Weinberger, Paul M., Ding, Ling-ling, Cowell, John K., Hudson, Farlyn Z., Ren, Mingqiang, Lee, Jeffrey R., Chen, Qi-kui, Su, Hong, Dynan, William S., Lin, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741053/
https://www.ncbi.nlm.nih.gov/pubmed/26847345
http://dx.doi.org/10.1186/s12885-016-2105-8

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