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Sex-dependent effects of developmental arsenic exposure on methylation capacity and methylation regulation of the glucocorticoid receptor system in the embryonic mouse brain
Previously we have shown that prenatal moderate arsenic exposure (50 ppb) disrupts glucocorticoid receptor (GR) programming and that these changes continue into adolescence in males. However, it was not clear what the molecular mechanisms were promoting these GR programming changes or if these chang...
Autores principales: | Allan, Andrea M., Hafez, Alexander K., Labrecque, Matthew T., Solomon, Elizabeth R., Shaikh, M. Nabil, Zheng, Xianyun, Ali, Abdulmehdi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741109/ https://www.ncbi.nlm.nih.gov/pubmed/26855884 http://dx.doi.org/10.1016/j.toxrep.2015.10.003 |
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