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A Comfort Survey of Timolol Hemihydrate 0.5% Solution Once or Twice Daily vs Timolol Maleate in Sorbate
Objective: To evaluate by survey the comfort upon instillation of timolol hemihydrate compared to timolol maleate with potassium sorbate. Design: A prospective, multicenter, observational, non-interventional study. Participants: One hundred and three patients of open-angle glaucoma or ocular hyperte...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Jaypee Brothers Medical Publishers
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741129/ https://www.ncbi.nlm.nih.gov/pubmed/26997774 http://dx.doi.org/10.5005/jp-journals-10008-1130 |
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author | Stewart, William C Oehler, Jeffrey C Choplin, Neil T Markoff, Joseph I Moster, Marlene R Ichhpujani, Parul Nelson, Lindsay A |
author_facet | Stewart, William C Oehler, Jeffrey C Choplin, Neil T Markoff, Joseph I Moster, Marlene R Ichhpujani, Parul Nelson, Lindsay A |
author_sort | Stewart, William C |
collection | PubMed |
description | Objective: To evaluate by survey the comfort upon instillation of timolol hemihydrate compared to timolol maleate with potassium sorbate. Design: A prospective, multicenter, observational, non-interventional study. Participants: One hundred and three patients of open-angle glaucoma or ocular hypertension who were ≥21 years old and were currently prescribed timolol hemihydrate (once or twice daily) or timolol maleate with potassium sorbate once daily as monotherapy or as a part of two-drug therapy. Materials and methods: Study was performed at seven clinical sites in the United States. Patients were surveyed on comfort upon instillation of timolol hemihydrate compared to timolol maleate with potassium sorbate. Results: A difference between timolol hemihydrate and timolol maleate with potassium sorbate for questions 1 (burning/stinging on instillation, p < 0.001) and 4 (tearing on instillation, p = 0.024) was noted. There were no differences between treatment groups for any other question (p > 0.05). Conclusion: This survey suggests that timolol hemihydrate is associated with less stinging/burning and tearing than timolol maleate with potassium sorbate. How to cite this article: Stewart WC, Oehler JC, Choplin NT, Markoff JI, Moster MR, Ichhpujani P, Nelson LA. A Comfort Survey of Timolol Hemihydrate 0.5% Solution Once or Twice Daily vs Timolol Maleate in Sorbate. J Current Glau Prac 2013;7(1):11-16. |
format | Online Article Text |
id | pubmed-4741129 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Jaypee Brothers Medical Publishers |
record_format | MEDLINE/PubMed |
spelling | pubmed-47411292016-03-18 A Comfort Survey of Timolol Hemihydrate 0.5% Solution Once or Twice Daily vs Timolol Maleate in Sorbate Stewart, William C Oehler, Jeffrey C Choplin, Neil T Markoff, Joseph I Moster, Marlene R Ichhpujani, Parul Nelson, Lindsay A J Curr Glaucoma Pract Original Article Objective: To evaluate by survey the comfort upon instillation of timolol hemihydrate compared to timolol maleate with potassium sorbate. Design: A prospective, multicenter, observational, non-interventional study. Participants: One hundred and three patients of open-angle glaucoma or ocular hypertension who were ≥21 years old and were currently prescribed timolol hemihydrate (once or twice daily) or timolol maleate with potassium sorbate once daily as monotherapy or as a part of two-drug therapy. Materials and methods: Study was performed at seven clinical sites in the United States. Patients were surveyed on comfort upon instillation of timolol hemihydrate compared to timolol maleate with potassium sorbate. Results: A difference between timolol hemihydrate and timolol maleate with potassium sorbate for questions 1 (burning/stinging on instillation, p < 0.001) and 4 (tearing on instillation, p = 0.024) was noted. There were no differences between treatment groups for any other question (p > 0.05). Conclusion: This survey suggests that timolol hemihydrate is associated with less stinging/burning and tearing than timolol maleate with potassium sorbate. How to cite this article: Stewart WC, Oehler JC, Choplin NT, Markoff JI, Moster MR, Ichhpujani P, Nelson LA. A Comfort Survey of Timolol Hemihydrate 0.5% Solution Once or Twice Daily vs Timolol Maleate in Sorbate. J Current Glau Prac 2013;7(1):11-16. Jaypee Brothers Medical Publishers 2013 2013-01-15 /pmc/articles/PMC4741129/ /pubmed/26997774 http://dx.doi.org/10.5005/jp-journals-10008-1130 Text en Copyright © 2013; Jaypee Brothers Medical Publishers (P) Ltd. This work is licensed under a Creative Commons Attribution 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by/3.0/ |
spellingShingle | Original Article Stewart, William C Oehler, Jeffrey C Choplin, Neil T Markoff, Joseph I Moster, Marlene R Ichhpujani, Parul Nelson, Lindsay A A Comfort Survey of Timolol Hemihydrate 0.5% Solution Once or Twice Daily vs Timolol Maleate in Sorbate |
title | A Comfort Survey of Timolol Hemihydrate 0.5% Solution Once or Twice Daily vs Timolol Maleate in Sorbate |
title_full | A Comfort Survey of Timolol Hemihydrate 0.5% Solution Once or Twice Daily vs Timolol Maleate in Sorbate |
title_fullStr | A Comfort Survey of Timolol Hemihydrate 0.5% Solution Once or Twice Daily vs Timolol Maleate in Sorbate |
title_full_unstemmed | A Comfort Survey of Timolol Hemihydrate 0.5% Solution Once or Twice Daily vs Timolol Maleate in Sorbate |
title_short | A Comfort Survey of Timolol Hemihydrate 0.5% Solution Once or Twice Daily vs Timolol Maleate in Sorbate |
title_sort | comfort survey of timolol hemihydrate 0.5% solution once or twice daily vs timolol maleate in sorbate |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741129/ https://www.ncbi.nlm.nih.gov/pubmed/26997774 http://dx.doi.org/10.5005/jp-journals-10008-1130 |
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