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Bulbar Conjunctival and Tenon's Layer Thickness Measurement using Optical Coherence Tomography

Purpose: Observations made during glaucoma filtering surgery (trabeculectomy) suggest variability in the thickness of the bulbar conjunctiva and Tenon's layers between individuals. We propose that this could infuence the final bleb morphology and function. We designed a pilot study to assess th...

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Autores principales: Howlett, J, Vahdani, K, Rossiter, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Jaypee Brothers Medical Publishers 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741171/
https://www.ncbi.nlm.nih.gov/pubmed/26997811
http://dx.doi.org/10.5005/jp-journals-10008-1163
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author Howlett, J
Vahdani, K
Rossiter, J
author_facet Howlett, J
Vahdani, K
Rossiter, J
author_sort Howlett, J
collection PubMed
description Purpose: Observations made during glaucoma filtering surgery (trabeculectomy) suggest variability in the thickness of the bulbar conjunctiva and Tenon's layers between individuals. We propose that this could infuence the final bleb morphology and function. We designed a pilot study to assess this using optical coherence tomography (OCT) to measure bulbar conjunctival and Tenon's layer thickness. Materials and methods: A total of 67 eyes of 48 individuals were scanned using an optovue Mode RT100 version 2.0 OCT machine. Cross-line CAM-L scans were taken and the com bined bulbar conjunctival and Tenon's layer thickness was measured 3 mm above the superior limbus. Conjunctival and Tenon's layers appeared as a hyper-refective section as opposed to the hypo refective underlying sclera. Measurements were taken using the inbuilt review software. Results: The age ranged from 23 to 91 years. There were 20 mal e s and 28 females. The mean conjunctival and Tenon's layer thick ness was 393 ± 67 microns (mean ± SD) ranging from 194 to 573 microns. Conclusion: Optical coherence tomography conjunctival and Tenon's layer thickness measurements appear to vary significantly between individuals. We postulate that this could infuence the final bleb morphology and may predict the risk of bleb encapsulation and failure or thin avascular blebs. Further assessment could establish cut-offs on which patients should receive intraoperative antimetabolites and/or Tenon's layer excision. How to cite this article: Howlett J, Vahdani K, Rossiter J. Bulbar Conjunctival and Tenon's Layer Thickness Measurement using Optical Coherence Tomography. J Curr Glaucoma Pract 2014;8(2):63-66.
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spelling pubmed-47411712016-03-18 Bulbar Conjunctival and Tenon's Layer Thickness Measurement using Optical Coherence Tomography Howlett, J Vahdani, K Rossiter, J J Curr Glaucoma Pract Original Research Purpose: Observations made during glaucoma filtering surgery (trabeculectomy) suggest variability in the thickness of the bulbar conjunctiva and Tenon's layers between individuals. We propose that this could infuence the final bleb morphology and function. We designed a pilot study to assess this using optical coherence tomography (OCT) to measure bulbar conjunctival and Tenon's layer thickness. Materials and methods: A total of 67 eyes of 48 individuals were scanned using an optovue Mode RT100 version 2.0 OCT machine. Cross-line CAM-L scans were taken and the com bined bulbar conjunctival and Tenon's layer thickness was measured 3 mm above the superior limbus. Conjunctival and Tenon's layers appeared as a hyper-refective section as opposed to the hypo refective underlying sclera. Measurements were taken using the inbuilt review software. Results: The age ranged from 23 to 91 years. There were 20 mal e s and 28 females. The mean conjunctival and Tenon's layer thick ness was 393 ± 67 microns (mean ± SD) ranging from 194 to 573 microns. Conclusion: Optical coherence tomography conjunctival and Tenon's layer thickness measurements appear to vary significantly between individuals. We postulate that this could infuence the final bleb morphology and may predict the risk of bleb encapsulation and failure or thin avascular blebs. Further assessment could establish cut-offs on which patients should receive intraoperative antimetabolites and/or Tenon's layer excision. How to cite this article: Howlett J, Vahdani K, Rossiter J. Bulbar Conjunctival and Tenon's Layer Thickness Measurement using Optical Coherence Tomography. J Curr Glaucoma Pract 2014;8(2):63-66. Jaypee Brothers Medical Publishers 2014 2014-06-12 /pmc/articles/PMC4741171/ /pubmed/26997811 http://dx.doi.org/10.5005/jp-journals-10008-1163 Text en Copyright © 2014; Jaypee Brothers Medical Publishers (P) Ltd. This work is licensed under a Creative Commons Attribution 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by/3.0/
spellingShingle Original Research
Howlett, J
Vahdani, K
Rossiter, J
Bulbar Conjunctival and Tenon's Layer Thickness Measurement using Optical Coherence Tomography
title Bulbar Conjunctival and Tenon's Layer Thickness Measurement using Optical Coherence Tomography
title_full Bulbar Conjunctival and Tenon's Layer Thickness Measurement using Optical Coherence Tomography
title_fullStr Bulbar Conjunctival and Tenon's Layer Thickness Measurement using Optical Coherence Tomography
title_full_unstemmed Bulbar Conjunctival and Tenon's Layer Thickness Measurement using Optical Coherence Tomography
title_short Bulbar Conjunctival and Tenon's Layer Thickness Measurement using Optical Coherence Tomography
title_sort bulbar conjunctival and tenon's layer thickness measurement using optical coherence tomography
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741171/
https://www.ncbi.nlm.nih.gov/pubmed/26997811
http://dx.doi.org/10.5005/jp-journals-10008-1163
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