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Structure of the human histone chaperone FACT Spt16 N-terminal domain

The histone chaperone FACT plays an important role in facilitating nucleosome assembly and disassembly during transcription. FACT is a heterodimeric complex consisting of Spt16 and SSRP1. The N-terminal domain of Spt16 resembles an inactive aminopeptidase. How this domain contributes to the histone...

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Detalles Bibliográficos
Autores principales:	Marcianò, G., Huang, D. T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Union of Crystallography 2016
Materias:	Research Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741192/ https://www.ncbi.nlm.nih.gov/pubmed/26841762 http://dx.doi.org/10.1107/S2053230X15024565

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