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Environment-Sensitive Fluorescent Probe for the Human Ether-a-go-go-Related Gene Potassium Channel

[Image: see text] A novel environment-sensitive probe S2 with turn-on switch for Human Ether-a-go-go-Related Gene (hERG) potassium channel was developed herein. After careful evaluation, this fluorescent probe showed high binding affinity with hERG potassium channel with an IC(50) value of 41.65 nM...

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Detalles Bibliográficos
Autores principales:	Liu, Zhenzhen, Jiang, Tianyu, Wang, Beilei, Ke, Bowen, Zhou, Yubin, Du, Lupei, Li, Minyong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2016
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741275/ https://www.ncbi.nlm.nih.gov/pubmed/26730746 http://dx.doi.org/10.1021/acs.analchem.5b04220

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