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Convergence of cMyc and β‐catenin on Tcf7l1 enables endoderm specification

The molecular machinery that directs formation of definitive endoderm from pluripotent stem cells is not well understood. Wnt/β‐catenin and Nodal signalling have been implicated, but the requirements for lineage specification remain incompletely defined. Here, we demonstrate a potent effect of inhib...

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Detalles Bibliográficos
Autores principales:	Morrison, Gillian, Scognamiglio, Roberta, Trumpp, Andreas, Smith, Austin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741304/ https://www.ncbi.nlm.nih.gov/pubmed/26675138 http://dx.doi.org/10.15252/embj.201592116

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