Imprint of 5-azacytidine on the natural killer cell repertoire during systemic treatment for high-risk myelodysplastic syndrome

5-azacytidine (5-aza) is a hypomethylating agent approved for the treatment of high-risk myelodysplastic syndrome (MDS). It is assumed to act by demethylating tumor suppressor genes and via direct cytotoxic effects on malignant cells. In vitro treatment with hypomethylating agents has profound effec...

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Detalles Bibliográficos
Autores principales: Sohlberg, Ebba, Pfefferle, Aline, Andersson, Sandra, Baumann, Bettina C., Hellström-Lindberg, Eva, Malmberg, Karl-Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper: Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741444/
https://www.ncbi.nlm.nih.gov/pubmed/26497557

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