Cargando…
TTK activates Akt and promotes proliferation and migration of hepatocellular carcinoma cells
Hepatocellular carcinoma (HCC) is one of the most malignant cancers with poor clinical outcome. The protein kinase human monopolar spindle 1 (hMps1/TTK) gene expression is significantly increased in HCCs. However, its contributions to hepatocarcinogenesis remain unclear. In this study, we found that...
Autores principales: | Liu, Xing, Liao, Weijia, Yuan, Qing, Ou, Ying, Huang, Jian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741454/ https://www.ncbi.nlm.nih.gov/pubmed/26418879 |
Ejemplares similares
-
Upregulation of FAM83D affects the proliferation and invasion of hepatocellular carcinoma
por: Liao, Weijia, et al.
Publicado: (2015) -
TTK regulates proliferation and apoptosis of gastric cancer cells through the Akt‐mTOR pathway
por: Huang, Hongxia, et al.
Publicado: (2020) -
Elongator promotes the migration and invasion of hepatocellular carcinoma cell by the phosphorylation of AKT
por: Xu, Yi, et al.
Publicado: (2018) -
CFI-402257, a TTK inhibitor, effectively suppresses hepatocellular carcinoma
por: Chan, Cerise Yuen-Ki, et al.
Publicado: (2022) -
Silencing of DLGAP5 by siRNA Significantly Inhibits the Proliferation and Invasion of Hepatocellular Carcinoma Cells
por: Liao, Weijia, et al.
Publicado: (2013)