Variation in human cancer cell external phosphatidylserine is regulated by flippase activity and intracellular calcium

Viable cancer cells expose elevated levels of phosphatidylserine (PS) on the exoplasmic face of the plasma membrane. However, the mechanisms leading to elevated PS exposure in viable cancer cells have not been defined. We previously showed that externalized PS may be used to monitor, target and kill...

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Detalles Bibliográficos
Autores principales: Vallabhapurapu, Subrahmanya D., Blanco, Víctor M., Sulaiman, Mahaboob K., Vallabhapurapu, Swarajya Lakshmi, Chu, Zhengtao, Franco, Robert S., Qi, Xiaoyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741459/
https://www.ncbi.nlm.nih.gov/pubmed/26462157

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