Evaluation of a novel human IgG1 anti-claudin3 antibody that specifically recognizes its aberrantly localized antigen in ovarian cancer cells and that is suitable for selective drug delivery

Membrane protein claudin3 has been recently suggested as a marker for biologically aggressive tumors and a possible target for the therapeutic delivery of active anti-cancer compounds. Claudin3-binding molecules such as the Clostridium perfringens enterotoxin (CPE), CPE-related molecules, and murine...

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Detalles Bibliográficos
Autores principales: Romani, Chiara, Cocco, Emiliano, Bignotti, Eliana, Moratto, Daniele, Bugatti, Antonella, Todeschini, Paola, Bandiera, Elisabetta, Tassi, Renata, Zanotti, Laura, Pecorelli, Sergio, Sartori, Enrico, Odicino, Franco E., de Marco, Ario, Davide Santin, Alessandro, Ravaggi, Antonella, Mitola, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741477/
https://www.ncbi.nlm.nih.gov/pubmed/26416446

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