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Next generation sequencing in synovial sarcoma reveals novel gene mutations
Over 95% of all synovial sarcomas (SS) share a unique translocation, t(X;18), however, they show heterogeneous clinical behavior. We analyzed multiple SS to reveal additional genetic alterations besides the translocation. Twenty-six SS from 22 patients were sequenced for 409 cancer-related genes usi...
Autores principales: | Vlenterie, Myrella, Hillebrandt-Roeffen, Melissa H.S., Flucke, Uta E., Groenen, Patricia J.T.A., Tops, Bastiaan B.J., Kamping, Eveline J., Pfundt, Rolph, de Bruijn, Diederik R.H., van Kessel, Ad H.M. Geurts, van Krieken, Han J.H.J.M., van der Graaf, Winette T.A., Versleijen-Jonkers, Yvonne M.H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741482/ https://www.ncbi.nlm.nih.gov/pubmed/26415226 |
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