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The knockdown of H19lncRNA reveals its regulatory role in pluripotency and tumorigenesis of human embryonic carcinoma cells
The function of imprinted H19 long non-coding RNA is still controversial. It is highly expressed in early embryogenesis and decreases after birth and re-expressed in cancer. To study the role of H19 in oncogenesis and pluripotency, we down-regulated H19 expression in vitro and in vivo in pluripotent...
Autores principales: | Zeira, Evelyne, Abramovitch, Rinat, Meir, Karen, Ram, Sharona Even, Gil, Yaniv, Bulvik, Baruch, Bromberg, Zohar, Levkovitch, Or, Nahmansson, Nathalie, Adar, Revital, Reubinoff, Benjamin, Galun, Eithan, Gropp, Michal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741483/ https://www.ncbi.nlm.nih.gov/pubmed/26415227 |
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