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Visualizing the antivascular effect of bortezomib on the hypoxic tumor microenvironment

Bortezomib, a novel proteasome inhibitor, has been approved for treating multiple myeloma and mantle cell lymphoma and studied pre-clinically and clinically for solid tumors. Preferential cytotoxicity of bortezomib was found toward hypoxic tumor cells and endothelial cells in vitro. The purpose of t...

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Detalles Bibliográficos
Autores principales:	Sun, Xiaorong, Ackerstaff, Ellen, He, Fuqiu, Xing, Ligang, Hsiao, Hung Tsung, Koutcher, Jason A., Ling, C. Clifton, Li, Gloria C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741486/ https://www.ncbi.nlm.nih.gov/pubmed/26416246

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