HPV16-E2 induces prophase arrest and activates the cellular DNA damage response in vitro and in precursor lesions of cervical carcinoma

Cervical intraepithelial neoplasia (CIN) is caused by human papillomavirus (HPV) infection and is the precursor to cervical carcinoma. The completion of the HPV productive life cycle depends on the expression of viral proteins which further determines the severity of the cervical neoplasia. Initiati...

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Detalles Bibliográficos
Autores principales: Xue, Yuezhen, Toh, Shen Yon, He, Pingping, Lim, Thimothy, Lim, Diana, Pang, Chai Ling, Abastado, Jean-Pierre, Thierry, Françoise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741503/
https://www.ncbi.nlm.nih.gov/pubmed/26474276

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