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High mitochondrial mass identifies a sub-population of stem-like cancer cells that are chemo-resistant
Chemo-resistance is a clinical barrier to more effective anti-cancer therapy. In this context, cancer stem-like cells (CSCs) are thought to be chemo-resistant, resulting in tumor recurrence and distant metastasis. Our hypothesis is that chemo-resistance in CSCs is driven, in part, by enhanced mitoch...
Autores principales: | Farnie, Gillian, Sotgia, Federica, Lisanti, Michael P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741545/ https://www.ncbi.nlm.nih.gov/pubmed/26421710 |
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