Discovery of Compound A – a selective activator of the glucocorticoid receptor with anti-inflammatory and anti-cancer activity

Glucocorticoids are among the most effective anti-inflammatory drugs, and are widely used for cancer therapy. Unfortunately, chronic treatment with glucocorticoids results in multiple side effects. Thus, there was an intensive search for selective glucocorticoid receptor (GR) activators (SEGRA), whi...

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Detalles Bibliográficos
Autores principales: Lesovaya, Ekaterina, Yemelyanov, Alexander, Swart, Amanda C., Swart, Pieter, Haegeman, Guy, Budunova, Irina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741564/
https://www.ncbi.nlm.nih.gov/pubmed/26436695

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