Colorectal cancer-related mutant KRAS alleles function as positive regulators of autophagy

The recent interest to modulate autophagy in cancer therapy has been hampered by the dual roles of this conserved catabolic process in cancer, highlighting the need for tailored approaches. Since RAS isoforms have been implicated in autophagy regulation and mutation of the KRAS oncogene is highly fr...

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Detalles Bibliográficos
Autores principales: Alves, Sara, Castro, Lisandra, Fernandes, Maria Sofia, Francisco, Rita, Castro, Paula, Priault, Muriel, Chaves, Susana Rodrigues, Moyer, Mary Pat, Oliveira, Carla, Seruca, Raquel, Côrte-Real, Manuela, Sousa, Maria João, Preto, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741568/
https://www.ncbi.nlm.nih.gov/pubmed/26418750

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