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Digital PCR analysis of plasma cell-free DNA for non-invasive detection of drug resistance mechanisms in EGFR mutant NSCLC: Correlation with paired tumor samples
As the development of resistance to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) has become an issue of concern, identification of the mechanisms responsible has become an urgent priority. However, for research purposes, it is not easy to obtain tumor samples from patien...
Autores principales: | Ishii, Hidenobu, Azuma, Koichi, Sakai, Kazuko, Kawahara, Akihiko, Yamada, Kazuhiko, Tokito, Takaaki, Okamoto, Isamu, Nishio, Kazuto, Hoshino, Tomoaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741572/ https://www.ncbi.nlm.nih.gov/pubmed/26334838 |
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