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Novel Axl-driven signaling pathway and molecular signature characterize high-grade ovarian cancer patients with poor clinical outcome

High-grade epithelial ovarian cancer (HGEOC) is a clinically diverse and molecularly heterogeneous disease comprising subtypes with distinct biological features and outcomes. The receptor tyrosine kinases, expressed by EOC cells, and their ligands, present in the microenvironment, activate signaling...

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Detalles Bibliográficos
Autores principales: Rea, Katia, Pinciroli, Patrizia, Sensi, Marialuisa, Alciato, Federica, Bisaro, Brigitte, Lozneanu, Ludmila, Raspagliesi, Francesco, Centritto, Floriana, Cabodi, Sara, Defilippi, Paola, Avanzi, Gian Carlo, Canevari, Silvana, Tomassetti, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741573/
https://www.ncbi.nlm.nih.gov/pubmed/26356564