Cargando…

Application of a patient-derived xenograft model in cytolytic viral activation therapy for nasopharyngeal carcinoma

Nasopharyngeal carcinoma (NPC) is an Epstein Barr virus (EBV)-related malignancy in which the tumor microenvironment plays a pivotal role in tumor progression. Here, we developed two patient-derived xenograft (PDX) mouse lines from engrafted NPC metastatic tumors. Positive staining for EBV-encoded s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hsu, Cheng-Lung, Kuo, Yung-Chia, Huang, Yenlin, Huang, Yin-Cheng, Lui, Kar-Wai, Chang, Kai-Ping, Lin, Tung-Liang, Fan, Hsien-Chi, Lin, An-Chi, Hsieh, Chia-Hsun, Lee, Li-Yu, Wang, Hung-Ming, Li, Hsin-Pai, Chang, Yu-Sun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741608/ https://www.ncbi.nlm.nih.gov/pubmed/26416517

Ejemplares similares

Nasopharyngeal carcinoma patient-derived xenograft mouse models reveal potential drugs targeting cell cycle, mTOR, and autophagy pathways
por: Li, Hsin-Pai, et al.
Publicado: (2023)

Combination of Epithelial Growth Factor Receptor Blockers and CDK4/6 Inhibitor for Nasopharyngeal Carcinoma Treatment
por: Li, Hsin-Pai, et al.
Publicado: (2021)

Correlation between overall survival and differential plasma and tissue tumor marker expression in nasopharyngeal carcinoma patients with different sites of organ metastasis
por: Wang, Hung-Ming, et al.
Publicado: (2016)

Integrated genomic analyses in PDX model reveal a cyclin-dependent kinase inhibitor Palbociclib as a novel candidate drug for nasopharyngeal carcinoma
por: Hsu, Cheng-Lung, et al.
Publicado: (2018)

Progesterone analogues reduce plasma Epstein–Barr virus DNA load and improve pain control in recurrent/metastatic nasopharyngeal carcinoma patients under supportive care
por: Hung, Chia-Yen, et al.
Publicado: (2017)

Aberrantly hypermethylated Homeobox A2 derepresses metalloproteinase-9 through TBP and promotes invasion in Nasopharyngeal carcinoma
por: Li, Hsin-Pai, et al.
Publicado: (2013)

Intensity Modulated Proton Beam Therapy versus Volumetric Modulated Arc Therapy for Patients with Nasopharyngeal Cancer: A Propensity Score-Matched Study
por: Chou, Yung-Chih, et al.
Publicado: (2021)

Cover the Patients’ Mouths While Obtaining Nasopharyngeal Specimens
por: Kao, Chia-Lung, et al.
Publicado: (2021)

A Novel KCNH2 S981fs Mutation Identified by Whole-Exome Sequencing Is Associated with Type 2 Long QT Syndrome
por: Cheng, Yu-Wen, et al.
Publicado: (2023)

Bacterial brain abscess in patients with nasopharyngeal carcinoma following radiotherapy: microbiology, clinical features and therapeutic outcomes
por: Fang, Peng-Hsiang, et al.
Publicado: (2012)

Circulating p16-Positive and p16-Negative Tumor Cells Serve as Independent Prognostic Indicators of Survival in Patients with Head and Neck Squamous Cell Carcinomas
por: Chang, Pei-Hung, et al.
Publicado: (2021)

The risk factors of the 72-h unscheduled return visit admission to emergency department in adults below 50 years old
por: Kao, Chia-Lung, et al.
Publicado: (2023)

Long-term effects on carotid intima-media thickness after radiotherapy in patients with nasopharyngeal carcinoma
por: Huang, Tai-Lin, et al.
Publicado: (2013)

Maintenance tegafur-plus-uracil after adjuvant concurrent chemoradiotherapy may improve outcome for resected oral cavity squamous cell carcinoma with extranodal extension
por: Huang, Pei-Wei, et al.
Publicado: (2022)

Development of a Monoclonal scFv against Cytotoxin to Neutralize Cytolytic Activity Induced by Naja atra Venom on Myoblast C2C12 Cells
por: Liu, Chien-Chun, et al.
Publicado: (2022)

PB2265: RISK FACTORS FOR DISEASE PROGRESSION OF MYCOSIS FUNGOIDES AND SÉZARY SYNDROME IN EAST ASIAN POPULATION
por: Wu, Huai-Chueh Gem, et al.
Publicado: (2023)

Activation of Multiple Apoptotic Pathways in Human Nasopharyngeal Carcinoma Cells by the Prenylated Isoflavone, Osajin
por: Huang, Tsung-Teng, et al.
Publicado: (2011)

Post-Irradiation Sinus Mucosa Disease in Nasopharyngeal Carcinoma Patients Treated with Intensity-Modulated Proton Therapy
por: Wu, Pei-Wen, et al.
Publicado: (2022)

A Patient-Derived Xenograft Model of Dedifferentiated Endometrial Carcinoma: A Proof-of-Concept Study for the Identification of New Molecularly Informed Treatment Approaches
por: Lin, Chiao-Yun, et al.
Publicado: (2021)

Association of type 2 diabetes with liver cirrhosis: a nationwide cohort study
por: Hsieh, Ping-Hsin, et al.
Publicado: (2017)

The Impact of Selenium Supplementation on Trauma Patients—Systematic Review and Meta-Analysis
por: Huang, Jen-Fu, et al.
Publicado: (2022)

Dehydrocrenatidine extracted from Picrasma quassioides induces the apoptosis of nasopharyngeal carcinoma cells through the JNK and ERK signaling pathways
por: Hsieh, Ming-Chang, et al.
Publicado: (2021)

Pinosylvin inhibits migration and invasion of nasopharyngeal carcinoma cancer cells via regulation of epithelial-mesenchymal transition and inhibition of MMP-2
por: Chuang, Yi-Ching, et al.
Publicado: (2021)

Inactivation of the tight junction gene CLDN11 by aberrant hypermethylation modulates tubulins polymerization and promotes cell migration in nasopharyngeal carcinoma
por: Li, Hsin-Pai, et al.
Publicado: (2018)

Association between coarse particulate matter (PM(10-2.5)) and nasopharyngeal carcinoma among Taiwanese men
por: Huang, Hsu-Chih, et al.
Publicado: (2020)

Serum Level of Tumor-Overexpressed AGR2 Is Significantly Associated with Unfavorable Prognosis of Canine Malignant Mammary Tumors
por: Yuan, Stephen Hsien-Chi, et al.
Publicado: (2021)

Cell type specificity of female lung cancer associated with sulfur dioxide from air pollutants in Taiwan: An ecological study
por: Tseng, Ching-Yu, et al.
Publicado: (2012)

Cinnamtannin B1 attenuates rosacea-like signs via inhibition of pro-inflammatory cytokine production and down-regulation of the MAPK pathway
por: Kan, Hung-Lin, et al.
Publicado: (2020)

Activin A regulates the epidermal growth factor receptor promoter by activating the PI3K/SP1 pathway in oral squamous cell carcinoma cells
por: Tsai, Chi-Neu, et al.
Publicado: (2019)

Risk of infection in neonates born in accidental out-of-hospital deliveries
por: Chang, Chia-Jung, et al.
Publicado: (2022)

Prospective comparison of early interim (18)F-FDG-PET with (18)F-FLT-PET for predicting treatment response and survival in metastatic breast cancer
por: Su, Tzu-Pei, et al.
Publicado: (2021)

Discovering the Clinical and Prognostic Role of Pan-Immune-Inflammation Values on Oral Cavity Squamous Cell Carcinoma
por: Yeh, Chia-Chi, et al.
Publicado: (2023)

Phorbol ester-induced angiogenesis of endothelial progenitor cells: The role of NADPH oxidase-mediated, redox-related matrix metalloproteinase pathways
por: Wu, Tao-Cheng, et al.
Publicado: (2019)

The Impact on the Clinical Prognosis of Low Serum Selenium Level in Patients with Severe Trauma: Systematic Review and Meta-Analysis
por: Chan, Shang-Yu, et al.
Publicado: (2022)

Purple urine bag syndrome in nursing homes: Ten elderly case reports and a literature review
por: Lin, Chi-Hung, et al.
Publicado: (2008)

Pharmacologically upregulated carcinoembryonic antigen-expression enhances the cytolytic activity of genetically-modified chimeric antigen receptor NK-92MI against colorectal cancer cells
por: Shiozawa, Masayuki, et al.
Publicado: (2018)

Attenuation of antigen-specific T helper 1 immunity by Neolitsea hiiranensis and its derived terpenoids
por: Cheng, Yin-Hua, et al.
Publicado: (2016)

Targeting annexin A2 reduces tumorigenesis and therapeutic resistance of nasopharyngeal carcinoma
por: Chen, Chang-Yu, et al.
Publicado: (2015)

Adenosine Receptor Modulates Permissiveness of Baculovirus (Budded Virus) Infection via Regulation of Energy Metabolism in Bombyx mori
por: Lin, Yu-Hsien, et al.
Publicado: (2020)

Detection of respiratory viruses in adults with respiratory tract infection using a multiplex PCR assay at a tertiary center
por: Tai, Cheng-Chun, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_0rkilf8nbff9svcb6gos4bn0i6