Proteolytic systems and AMP-activated protein kinase are critical targets of acute myeloid leukemia therapeutic approaches

The therapeutic strategies against acute myeloid leukemia (AML) have hardly been modified over four decades. Although resulting in a favorable outcome in young patients, older individuals, the most affected population, do not respond adequately to therapy. Intriguingly, the mechanisms responsible fo...

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Detalles Bibliográficos
Autores principales: Fernandes, Ângela, Azevedo, Maria M., Pereira, Olga, Sampaio-Marques, Belém, Paiva, Artur, Correia-Neves, Margarida, Castro, Isabel, Ludovico, Paula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741616/
https://www.ncbi.nlm.nih.gov/pubmed/25537507

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