Integrated gene and miRNA expression analysis of prostate cancer associated fibroblasts supports a prominent role for interleukin-6 in fibroblast activation

Tumor microenvironment coevolves with and simultaneously sustains cancer progression. In prostate carcinoma (PCa), cancer associated fibroblasts (CAF) have been shown to fuel tumor development and metastasis by mutually interacting with tumor cells. Molecular mechanisms leading to activation of CAFs...

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Detalles Bibliográficos
Autores principales: Doldi, Valentina, Callari, Maurizio, Giannoni, Elisa, D'Aiuto, Francesca, Maffezzini, Massimo, Valdagni, Riccardo, Chiarugi, Paola, Gandellini, Paolo, Zaffaroni, Nadia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741617/
https://www.ncbi.nlm.nih.gov/pubmed/26375444

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