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BCAT1 expression associates with ovarian cancer progression: possible implications in altered disease metabolism

Previously, we have identified the branched chain amino-acid transaminase 1 (BCAT1) gene as notably hypomethylated in low-malignant potential (LMP) and high-grade (HG) serous epithelial ovarian tumors, compared to normal ovarian tissues. Here we show that BCAT1 is strongly overexpressed in both LMP...

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Detalles Bibliográficos
Autores principales: Wang, Zhi-Qiang, Faddaoui, Adnen, Bachvarova, Magdalena, Plante, Marie, Gregoire, Jean, Renaud, Marie-Claude, Sebastianelli, Alexandra, Guillemette, Chantal, Gobeil, Stéphane, Macdonald, Elizabeth, Vanderhyden, Barbara, Bachvarov, Dimcho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741622/
https://www.ncbi.nlm.nih.gov/pubmed/26372729