Prognostic significance of K-Ras mutation rate in metastatic colorectal cancer patients

Introduction: Activating mutations of K-Ras gene have a well-established role as predictors of resistance to anti-EGFR monoclonal antibodies in metastatic colorectal cancer (mCRC) patients. Their prognostic value is controversial, and no data regarding the prognostic value of mutation rate, defined...

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Detalles Bibliográficos
Autores principales: Vincenzi, Bruno, Cremolini, Chiara, Sartore-Bianchi, Andrea, Russo, Antonio, Mannavola, Francesco, Perrone, Giuseppe, Pantano, Francesco, Loupakis, Fotios, Rossini, Daniele, Ongaro, Elena, Bonazzina, Erica, Dell'Aquila, Emanuela, Imperatori, Marco, Zoccoli, Alice, Bronte, Giuseppe, De Maglio, Giovanna, Fontanini, Gabriella, Natoli, Clara, Falcone, Alfredo, Santini, Daniele, Onetti-Muda, Andrea, Siena, Salvatore, Tonini, Giuseppe, Aprile, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741627/
https://www.ncbi.nlm.nih.gov/pubmed/26384309

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