A four gene signature predicts benefit from anthracyclines: evidence from the BR9601 and MA.5 clinical trials

Chromosome instability (CIN) in solid tumours results in multiple numerical and structural chromosomal aberrations and is associated with poor prognosis in multiple tumour types. Recent evidence demonstrated CEP17 duplication, a CIN marker, is a predictive marker of anthracycline benefit. An analysi...

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Detalles Bibliográficos
Autores principales: Spears, Melanie, Yousif, Fouad, Lyttle, Nicola, Boutros, Paul C., Munro, Alison F., Twelves, Chris, Pritchard, Kathleen I., Levine, Mark N., Shepherd, Lois, Bartlett, John MS.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741633/
https://www.ncbi.nlm.nih.gov/pubmed/26372731

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