Non-random aneuploidy specifies subgroups of pilocytic astrocytoma and correlates with older age

Pilocytic astrocytoma (PA) is the most common brain tumor in children but is rare in adults, and hence poorly studied in this age group. We investigated 222 PA and report increased aneuploidy in older patients. Aneuploid genomes were identified in 45% of adult compared with 17% of pediatric PA. Gain...

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Detalles Bibliográficos
Autores principales: Fontebasso, Adam M., Shirinian, Margret, Khuong-Quang, Dong-Anh, Bechet, Denise, Gayden, Tenzin, Kool, Marcel, De Jay, Nicolas, Jacob, Karine, Gerges, Noha, Hutter, Barbara, Şeker-Cin, Huriye, Witt, Hendrik, Montpetit, Alexandre, Brunet, Sébastien, Lepage, Pierre, Bourret, Geneviève, Klekner, Almos, Bognár, László, Hauser, Peter, Garami, Miklós, Farmer, Jean-Pierre, Montes, Jose-Luis, Atkinson, Jeffrey, Lambert, Sally, Kwan, Tony, Korshunov, Andrey, Tabori, Uri, Collins, V. Peter, Albrecht, Steffen, Faury, Damien, Pfister, Stefan M., Paulus, Werner, Hasselblatt, Martin, Jones, David T.W., Jabado, Nada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741644/
https://www.ncbi.nlm.nih.gov/pubmed/26378811

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