A constitutive active MAPK/ERK pathway due to BRAF(V600E) positively regulates AHR pathway in PTC

The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor mediating the toxicity and tumor-promoting properties of dioxin. AHR has been reported to be overexpressed and constitutively active in a variety of solid tumors, but few data are currently available concerning its role i...

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Detalles Bibliográficos
Autores principales: Occhi, Gianluca, Barollo, Susi, Regazzo, Daniela, Bertazza, Loris, Galuppini, Francesca, Guzzardo, Vincenza, Jaffrain-Rea, Marie Lise, Vianello, Federica, Ciato, Denis, Ceccato, Filippo, Watutantrige-Fernando, Sara, Bisognin, Andrea, Bortoluzzi, Stefania, Pennelli, Gianmaria, Boscaro, Marco, Scaroni, Carla, Mian, Caterina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741662/
https://www.ncbi.nlm.nih.gov/pubmed/26392334

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