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Hypoxia-induced endoplasmic reticulum stress characterizes a necrotic phenotype of pancreatic cancer

Stromal fibrosis and tissue necrosis are major histological sequelae of hypoxia. The hypoxia-to-fibrosis sequence is well-documented in pancreatic ductal adenocarcinoma (PDAC). However, hypoxic and necrotic PDAC phenotypes are insufficiently characterized. Recently, reduction of tuberous sclerosis e...

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Detalles Bibliográficos
Autores principales:	Kong, Bo, Cheng, Tao, Wu, Weiwei, Regel, Ivonne, Raulefs, Susanne, Friess, Helmut, Erkan, Mert, Esposito, Irene, Kleeff, Jörg, Michalski, Christoph W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741665/ https://www.ncbi.nlm.nih.gov/pubmed/26452217

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