MiR-373 drives the epithelial-to-mesenchymal transition and metastasis via the miR-373-TXNIP-HIF1α-TWIST signaling axis in breast cancer

Our previous proteomics study revealed that thioredoxin-interacting protein (TXNIP) was down-regulated by miR-373. However, little is known of the mechanism by which miR-373 decreases TXNIP to stimulate metastasis. In this study, we show that miR-373 promotes the epithelial-to-mesenchymal transition...

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Detalles Bibliográficos
Autores principales: Chen, De, Dang, Bian-Li, Huang, Jin-zhou, Chen, Min, Wu, Di, Xu, Man-Li, Li, Rong, Yan, Guang-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741723/
https://www.ncbi.nlm.nih.gov/pubmed/26196741

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