Cargando…

Breast cancer associated a2 isoform vacuolar ATPase immunomodulates neutrophils: potential role in tumor progression

In invasive breast cancer, tumor associated neutrophils (TAN) represent a significant portion of the tumor mass and are associated with increased angiogenesis and metastasis. Identifying the regulatory factors that control TAN behavior will help in developing ideal immunotherapies. Vacuolar ATPases...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ibrahim, Safaa A., Katara, Gajendra K., Kulshrestha, Arpita, Jaiswal, Mukesh K., Amin, Magdy A., Beaman, Kenneth D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741747/ https://www.ncbi.nlm.nih.gov/pubmed/26460736

Ejemplares similares

Cancer derived peptide of vacuolar ATPase ‘a2’ isoform promotes neutrophil migration by autocrine secretion of IL-8
por: Ibrahim, Safaa A., et al.
Publicado: (2016)

Vacuolar ATPase ‘a2’ isoform exhibits distinct cell surface accumulation and modulates matrix metalloproteinase activity in ovarian cancer
por: Kulshrestha, Arpita, et al.
Publicado: (2015)

The curious case of vacuolar ATPase: regulation of signaling pathways
por: Pamarthy, Sahithi, et al.
Publicado: (2018)

Cancer‐associated V‐ATPase induces delayed apoptosis of protumorigenic neutrophils
por: Ibrahim, Safaa A., et al.
Publicado: (2020)

The Vacuolar ATPase a2-subunit regulates Notch signaling in triple-negative breast cancer cells
por: Pamarthy, Sahithi, et al.
Publicado: (2015)

Identification of Novel Bisbenzimidazole Derivatives as Anticancer Vacuolar (H(+))-ATPase Inhibitors †
por: Patil, Renukadevi, et al.
Publicado: (2017)

Targeting V-ATPase Isoform Restores Cisplatin Activity in Resistant Ovarian Cancer: Inhibition of Autophagy, Endosome Function, and ERK/MEK Pathway
por: Kulshrestha, Arpita, et al.
Publicado: (2019)

Hematopoietic stem cell specific V-ATPase controls breast cancer progression and metastasis via cytotoxic T cells
por: Sahoo, Manoranjan, et al.
Publicado: (2018)

Mammary epithelium‐specific inactivation of V‐ATPase reduces stiffness of extracellular matrix and enhances metastasis of breast cancer
por: Katara, Gajendra K., et al.
Publicado: (2017)

Interleukin‐22 promotes development of malignant lesions in a mouse model of spontaneous breast cancer
por: Katara, Gajendra K., et al.
Publicado: (2019)

Microtubule inhibitor, SP-6-27 inhibits angiogenesis and induces apoptosis in ovarian cancer cells
por: Kulshrestha, Arpita, et al.
Publicado: (2017)

The V-ATPase a2 isoform controls mammary gland development through Notch and TGF-β signaling
por: Pamarthy, Sahithi, et al.
Publicado: (2016)

In vivo anti‐V‐ATPase antibody treatment delays ovarian tumor growth by increasing antitumor immune responses
por: Kulshrestha, Arpita, et al.
Publicado: (2020)

Notch Signaling in Inflammation-Induced Preterm Labor
por: Jaiswal, Mukesh K., et al.
Publicado: (2015)

Expression of a2 Vacuolar ATPase in Spermatozoa is Associated with Semen Quality and Chemokine-Cytokine Profiles in Infertile Men
por: Ota, Kuniaki, et al.
Publicado: (2013)

An isoform of the vacuolar (H(+))-ATPase accessory subunit Ac45
por: Jansen, Eric J. R., et al.
Publicado: (2009)

Altered autophagic flux enhances inflammatory responses during inflammation-induced preterm labor
por: Agrawal, Varkha, et al.
Publicado: (2015)

The vacuolar-ATPase (V-ATPase) modulates matrix metalloproteinase (MMP) isoforms in human pancreatic cancer
por: Chung, Chuhan, et al.
Publicado: (2011)

An independent endocytic pathway stimulates different monocyte subsets by the a2 N-terminus domain of vacuolar-ATPase
por: Kwong, Christina, et al.
Publicado: (2013)

Conditional Deletion of the V-ATPase a2-Subunit Disrupts Intrathymic T Cell Development
por: Peterson, Theodore V., et al.
Publicado: (2019)

Extracellular and Luminal pH Regulation by Vacuolar H(+)-ATPase Isoform Expression and Targeting to the Plasma Membrane and Endosomes
por: Smith, Gina A., et al.
Publicado: (2016)

The a subunit isoforms of vacuolar-type proton ATPase exhibit differential distribution in mouse perigastrulation embryos
por: Sun-Wada, Ge-Hong, et al.
Publicado: (2022)

Role of the vacuolar ATPase in the Alphavirus replication cycle
por: Schuchman, Ryan M., et al.
Publicado: (2018)

Rotating with the brakes on and other unresolved features of the vacuolar ATPase
por: Rawson, Shaun, et al.
Publicado: (2016)

Flexibility within the Rotor and Stators of the Vacuolar H(+)-ATPase
por: Song, Chun Feng, et al.
Publicado: (2013)

Advances in targeting the vacuolar proton-translocating ATPase (V-ATPase) for anti-fungal therapy
por: Hayek, Summer R., et al.
Publicado: (2014)

The vacuolar H+ ATPase is a novel therapeutic target for glioblastoma
por: Di Cristofori, Andrea, et al.
Publicado: (2015)

Cryo-EM studies of the structure and dynamics of vacuolar-type ATPases
por: Mazhab-Jafari, Mohammad T., et al.
Publicado: (2016)

Vacuolar-type ATPase: A proton pump to lysosomal trafficking
por: FUTAI, Masamitsu, et al.
Publicado: (2019)

RNA Interference of Genes Encoding the Vacuolar-ATPase in Liriomyza trifolii
por: Chang, Ya-Wen, et al.
Publicado: (2021)

Isoform a4 of the vacuolar ATPase a subunit promotes 4T1-12B breast cancer cell–dependent tumor growth and metastasis in vivo
por: Su, Kevin, et al.
Publicado: (2022)

Molecular and functional characterization of vacuolar-ATPase from the American dog tick Dermacentor variabilis
por: Petchampai, N, et al.
Publicado: (2014)

Acidification of the lysosome-like vacuole and the vacuolar H+-ATPase are deficient in two yeast mutants that fail to sort vacuolar proteins
Publicado: (1989)

The a3 isoform of subunit a of the vacuolar ATPase localizes to the plasma membrane of invasive breast tumor cells and is overexpressed in human breast cancer
por: Cotter, Kristina, et al.
Publicado: (2016)

Probing Subunit-Subunit Interactions in the Yeast Vacuolar ATPase by Peptide Arrays
por: Parsons, Lee S., et al.
Publicado: (2012)

Vacuolar H(+)-ATPase is not restricted to clear cells of the epididymal epithelium in cattle
por: Kim, Sung Woo, et al.
Publicado: (2021)

The role of Plasmodium V-ATPase in vacuolar physiology and antimalarial drug uptake
por: Alder, Arne, et al.
Publicado: (2023)

Purification of active human vacuolar H(+)-ATPase in native lipid-containing nanodiscs
por: Oot, Rebecca A., et al.
Publicado: (2021)

Structure of the Vacuolar H(+)-ATPase Rotary Motor Reveals New Mechanistic Insights
por: Rawson, Shaun, et al.
Publicado: (2015)

Covalent Targeting of the Vacuolar H(+)-ATPase Activates Autophagy Via mTORC1 Inhibition
por: Yik-Sham Chung, Clive, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_rg2ejr25uhqf7fm4ur3kbn1oe1