Vesicular stomatitis virus expressing interferon-β is oncolytic and promotes antitumor immune responses in a syngeneic murine model of non-small cell lung cancer

Vesicular stomatitis virus (VSV) is a potent oncolytic virus for many tumors. VSV that produces interferon-β (VSV-IFNβ) is now in early clinical testing for solid tumors. Here, the preclinical activity of VSV and VSV-IFNβ against non-small cell lung cancer (NSCLC) is reported. NSCLC cell lines were...

Descripción completa

Detalles Bibliográficos
Autores principales: Patel, Manish R., Jacobson, Blake A., Ji, Yan, Drees, Jeremy, Tang, Shaogeng, Xiong, Kerry, Wang, Hengbing, Prigge, Jennifer E., Dash, Alexander S., Kratzke, Andrea K., Mesev, Emily, Etchison, Ryan, Federspiel, Mark J., Russell, Stephen J., Kratzke, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741756/
https://www.ncbi.nlm.nih.gov/pubmed/26431376

Ejemplares similares

Ejemplares similares