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An epigenetic auto-feedback loop regulates TGF-β type II receptor expression and function in NSCLC
The downregulation of transforming growth factor-β (TGF-β) type II receptor (TβRII) expression and function plays a pivotal role in the loss of the TGF-β-induced tumor suppressor function that contributes to lung cancer progression. The aberrant expression of miRNAs has been shown to be involved in...
Autores principales: | Yang, Shanzhong, Cho, Yong-Jig, Jin, Lin, Yuan, Guandou, Datta, Arunima, Buckhaults, Phillip, Datta, Pran K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741762/ https://www.ncbi.nlm.nih.gov/pubmed/26356817 |
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