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Liver X receptor reduces proliferation of human oral cancer cells by promoting cholesterol efflux via up-regulation of ABCA1 expression
Liver X receptors (LXRs) contribute not only to maintain cholesterol homeostasis but also to control cell growth. However, the molecular mechanisms behind the LXR-mediated anti-proliferative effects are largely unknown. Here we show, by immunohistochemistry, that LXRα and LXRβ are differentially dis...
Autores principales: | Kaneko, Tetsuharu, Kanno, Chihiro, Ichikawa-Tomikawa, Naoki, Kashiwagi, Korehito, Yaginuma, Nanae, Ohkoshi, Chihiro, Tanaka, Mizuko, Sugino, Takashi, Imura, Tetsuya, Hasegawa, Hiroshi, Chiba, Hideki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741770/ https://www.ncbi.nlm.nih.gov/pubmed/26452260 |
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