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CD19(+)CD24(hi)CD38(hi)Bregs involved in downregulate helper T cells and upregulate regulatory T cells in gastric cancer
Regulatory B cells (Bregs) play a critical role in inflammation and autoimmune disease. We characterized the role of Bregs in the progression of gastric cancer. We detected an increase in Bregs producing IL-10 both in peripheral blood mononuclear cells (PBMCs) and in gastric tumors. Multicolor flow...
Autores principales: | Wang, Weiwei, Yuan, Xiangliang, Chen, Hui, Xie, Guohua, Ma, Yanhui, Zheng, Yingxia, Zhou, Yunlan, Shen, Lisong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741780/ https://www.ncbi.nlm.nih.gov/pubmed/26378021 |
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