MT1-MMP dependent repression of the tumor suppressor SPRY4 contributes to MT1-MMP driven melanoma cell motility

Metastatic melanoma is the deadliest of all skin cancers. Despite progress in diagnostics and treatment of melanoma, the prognosis for metastatic patients remains poor. We previously showed that Membrane-type 1 Matrix Metalloproteinase (MT1-MMP) is one of the drivers of melanoma metastasis. Classica...

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Detalles Bibliográficos
Autores principales: Shaverdashvili, Khvaramze, Zhang, Keman, Osman, Iman, Honda, Kord, Jobava, Rauli, Bedogni, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741782/
https://www.ncbi.nlm.nih.gov/pubmed/26392417

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